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CyberpoliSickle cell diseaseFrequently asked questionsTreatment of severe sickle cell diseaseCan a stem cell and bone marrow transplantation cure sickle cell disease?

Frequently asked question: Can a stem cell and bone marrow transplantation cure sickle cell disease?

Sickle cell disease is a hereditary condition that can only be cured by replacing a patient’s bone marrow with donor bone marrow.
This is called a stem cell or bone marrow transplant, which is an intensive and complex procedure that replaces the patient’s entire red blood cell production infrastructure with that of a donor. The new produced red blood cells will not have hemoglobin with an abnormal beta globin chain, but instead have normal beta globin chains, which means that normal hemoglobin A1 will be produced. In the Netherlands, there is considerable experience with this kind of transplant. However, it is rarely used in cases of sickle cell disease, because the adverse effects and risks still outweigh the benefits.

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Relevant medical information

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Ask your question about Sickle cell disease to an expert

Treatment of severe sickle cell disease

Can a stem cell and bone marrow transplantation cure sickle cell disease?
How are severe cases of sickle cell disease treated?
What are the downsides of repeated blood transfusions for sickle cell disease?
What are the effects of an exchange transfusion?
What effect does a blood transfusion have on sickle cell disease?
What triggers an immune reaction?
When will treatment include blood transfusions or exchange transfusions?

Other subjects

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General

Medication and sickle cell disease

Occurrence of sickle cell disease

Sickle cell disease and pregnancy

Sickle cell disease symptoms and problems

The hereditary nature of sickle cell disease

The problem with hemoglobin S

The role and structure of hemoglobin

The sickle cell disease diagnosis

Traveling with sickle cell disease

Treatment of severe sickle cell disease

Treatment of sickle cell disease; prevention, treatment, and support

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